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Dust buildup isn't always as risky as people think - most consoles handle it fine until airflow really suffers. Compressed air works best, just keep the can upright and use short bursts from a few inches away, or grab a soft-bristled brush if you want to be extra cautious.
The thing people often miss is that you want to prevent the fan from spinning while you're blowing air at it. If you just hit those vents with compressed air, the fan blades can whip around and potentially damage the motor or bearings - especially on older units. Hold the console steady, maybe even gently wedge something to keep internal fans from moving if you can access the area, then use short bursts from a distance of a few inches. Keep the can perfectly upright so you're only getting the propellant gas, not liquid, which would be bad news.
For tougher buildup that won't budge with air alone, a soft brush or old toothbrush works wonders on the vent grilles themselves. Just be gentle and work around the vents rather than pushing bristles into them. If dust has really packed in there, sometimes a slightly damp microfiber cloth dabbed around the outside helps, but keep any moisture far away from openings - dry is always safer with electronics. The key is patience over aggression, really.
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