Dry eye symptoms actually get worse the longer you stare without moving, because you blink about 66% less when focusing on a screen compared to normal conversation. So while everyone's touching on real factors here, the order matters - you need to attack this systematically rather than trying one fix and hoping.
Start with the blink-and-movement piece since that's the fastest win. Set a timer for every 20 minutes and genuinely look away at something across the room. While you're doing that, consciously blink a few times. It sounds mechanical, but your eyes literally dry out when you're locked in, and no amount of monitor tweaking fixes that. If afternoon blur is your main complaint, this alone often makes a huge difference within a few days.
Then layer in the lighting. Your room's ambient light matters as much as what's on screen - if you're in a dim space with a bright monitor, your pupils are constantly dilating and contracting, which is exhausting over hours. Grab a desk lamp or adjust your room brightness so there's less contrast. Position your monitor about arm's length away and slightly below eye level; closer isn't better, and looking slightly downward is more natural. Finally, if your eyes still feel sandy by afternoon, artificial tears designed for dry eye (not the basic redness-relief ones) can help, especially brands made for screen time. Most people find that the combo of frequent breaks, better lighting balance, and actually remembering to blink does the job without needing expensive monitor upgrades.