Can I take ibuprofen with my blood pressure medication?

Question

I've been on lisinopril for about a year now and my doctor never really went over drug interactions. I usually grab ibuprofen when I have a headache or sore muscles from the gym, but I'm wondering if that's actually safe to combine with my BP meds. Should I be using something else instead?

Answer 1 · 2026-07-25T09:49:03.894212+03:00

You really need to call your doctor or pharmacist before taking ibuprofen with lisinopril, since NSAIDs can reduce how well ACE inhibitors work and potentially affect your kidney function. In the meantime, acetaminophen is usually a safer bet for headaches and muscle soreness if you need something quickly.

Can I take ibuprofen with my blood pressure medication?

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