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All heartburn medications work by one of two principles: either they neutralize acid (antacids like Rennie or Gaviscon), or they reduce its production (omeprazole, ranitidine). Antacids work quickly, but don't last long - they're good for occasional flare-ups, while acid blockers work more slowly but give you longer-lasting relief. If heartburn bothers you rarely, grab a regular antacid; if it's frequent, it's better to talk to a doctor, because there might be a more serious problem and you'll need a longer-acting medication that needs monitoring.

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