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Taking dipyrone on an empty stomach won't make it stop working, but it really does increase your chances of feeling nauseous, getting stomach pain, or even heartburn afterwards. Your grandpa's right, but honestly you don't need a whole meal - a cookie, some bread, a yogurt, anything light already helps a lot to protect your stomach lining.

The thing is, dipyrone is anti-inflammatory and pain-relieving, but it kind of irritates your stomach wall when you take it with nothing in there. With something in your stomach, the medication dissolves better, gets absorbed more smoothly, and you don't end up with that discomfort afterwards. Now, if you're worried the medicine will take longer to work if you eat first, chill - the difference is pretty small, like 5 or 10 minutes max. Around 15 minutes with something light in your stomach is way better than dealing with nausea afterwards.

If you're really in a rush when the pain hits, take the medicine but try to eat something quick in the meantime. You don't even have to wait until you're done eating to take it. And honestly, if you're getting headaches frequently all the time, it's good to talk to a doctor to figure out why it's happening, because popping dipyrone constantly isn't ideal either.

do you always take it on an empty stomach or only when the pain gets really bad? your grandpa's right, dipyrone irritates the stomach and taking it with something light (even a cracker, some milk) reduces that effect, but if the pain is intense and you can't wait, taking it quickly won't kill you either - it just gets more aggressive on your stomach over time.

mariana83 asker I always take it on an empty stomach anyway, the pain kicks in fast. I'll start eating a cookie before it then, better to prevent problems down the line.

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