It's not really about which assistant is "better" - it's more about which fits your working style. All the major models (ChatGPT, Claude, Gemini, and others) handle Python pretty well, they just differ in the details: one explains concepts better, another catches syntax errors faster, a third handles large code files more smoothly.
From my experience, Claude is worth trying - he's usually more careful with logic and acknowledges his own mistakes (like "I might have missed this or that"), which helps you figure things out yourself. With Python errors, he often gives not just a fix but explains why the mistake happened. ChatGPT is solid too, but sometimes it gives confident answers that sound more convincing than they actually are. GitHub Copilot works right in your editor - handy if your scripts are short and routine, but for debugging complex errors you're better off with a full chat.
Here's honest advice: take a couple of similar tasks (like data parsing or text processing) and run them through two or three assistants at once. See whose error explanations make the most sense to you and whose code is easiest to read. After that, you'll know who to pick for your workflow.