The timing thing is actually important - have you tried waiting until she's really hungry but not absolutely frantic? Sometimes babies are more open to trying new things when they're calm enough to explore rather than panicking. Also, temperature matters more than you'd think; some babies reject bottles that are too cold or too warm, so experiment with warming it to body temperature or even slightly warmer. One thing that helped people I know was having someone else (not you) offer the bottle while you're out of the room - babies can smell breastmilk and associate you with the breast, so sometimes a partner or caregiver has better luck. What specific nipple flow are you using, and have you tried expressed milk versus formula in the bottle?