Refusing food for three days is already a serious warning sign, not just boredom. Guinea pigs' digestion works continuously, and when they stop eating, it quickly leads to serious complications, so you shouldn't wait. Lethargy, loss of appetite, unwillingness to move can indicate an infection, dental problems, gas buildup in the intestines, or other conditions that require a specialist's examination.
You need to take her to the vet the very next day or even today if it's possible. During the consultation, the vet will figure out what's going on - check her teeth, listen to her belly, take tests if needed. In the meantime - offer her something soft and appealing (carrot, apple, cucumber) so at least something gets into her system, and make sure she's drinking water at least.